Product Guides / Supplements & Nutrition
NAD+ Supplements and IV Guide
Humanic Blue’s Longevity365 guide: NAD+ marketing can lead to a capsule, a prescription vitamin or an infusion appointment. Those are different products and routes. This comparison explains what the five named offerings contain and how the sellers describe them.
Explore the productsNAD+ is a molecule involved in reactions that help cells use energy. That makes it a subject of research on aging, but it does not make every NAD+-related product the same route to living longer. The starting point is identifying what is actually being offered.
01 / Our approach
How did we evaluate these products and services?
We compared the compound, delivery route and seller-described purpose. NR means nicotinamide riboside; NMN means nicotinamide mononucleotide. These are compounds the body can use in making NAD+. Company claims are attributed rather than treated as independently established results.
NAD+ Supplements: evidence and sources02 / The takeaways
What did the source evidence show?
- Tru Niagen’s selected capsule contains NR. Basis adds pterostilbene to NR, while Renue’s selected liposomal capsule contains NMN.
- NADclinic describes an infusion service delivered through medical professionals; the local provider and exact service matter.
- Niacor is prescription nicotinic acid for labeled medical uses, not a consumer NAD+ longevity supplement.
What changes when two products use different compounds despite sharing NAD+ in their descriptions?
What safety context matters here?
FDA has received reports of severe chills, shaking, vomiting and fatigue after NAD+ injectable drugs, with some cases requiring medical treatment. Its warning concerns ingredients unsuitable for sterile compounding. These reports concern the product category; they do not establish that a named provider caused the reported events. Primary source
The products and services
What is distinct about each product or service?
The order is not a ranking. Each profile describes the named offering and the differences that matter in this comparison.
Product 01 / 05
Tru Niagen 300 mg
Manufacturer label300 mg NR chloride per capsule
Tru Niagen’s selected 300 mg product contains nicotinamide riboside chloride in a vegetarian capsule. The company markets it for raising NAD+ and supporting cellular health. Its 300 mg capsule should not be confused with other Tru Niagen strengths or products.
The seller offers different bottle counts and optional recurring purchases. The relevant comparison is the selected capsule and the full purchase terms, rather than an introductory subscription discount on its own.
Product 02 / 05
Elysium Basis
Manufacturer label250 mg NR + 50 mg pterostilbene per two capsules
Elysium Basis combines 250 mg NR with 50 mg pterostilbene per two capsules. Elysium says the formula supports cellular health by raising NAD+. Pterostilbene is the second named ingredient; the formula is not equivalent to NR alone.
Elysium offers one-time purchases and recurring plans. It warns against use during pregnancy or nursing. Prepaid plans have a commitment covering the selected term, which differs from a cancellable monthly purchase.
Product 03 / 05
Renue by Science NMN Liposomal Capsules
Manufacturer label500 mg NMN per two capsules
Renue’s liposomal NMN capsules list 500 mg NMN per two-capsule serving, or 250 mg per capsule. The company claims its liposomal formulation improves delivery and supports cellular energy. Liposomal describes a formulation using fat-based structures; the label also lists sunflower lecithin.
Renue’s plain NMN powder is a separate offering with a different formulation and serving measure. The capsule name and the correct product link distinguish the two.
Product 04 / 05
NADclinic IV NAD+ therapy
Company-described serviceProvider network offering IV NAD+ services
NADclinic describes a network of medical professionals providing intravenous NAD+ services. Intravenous means delivery into a vein. Its company-wide description does not specify one universal infusion amount, local practitioner or appointment price.
The exact clinic, professional oversight and formulation determine what an appointment includes. The FDA’s sterile-compounding warning above concerns injectable NAD+ generally; it is not an allegation that NADclinic caused the reported events.
Product 05 / 05
Niacor 500 mg nicotinic acid tablets — prescription comparator
Prescription product informationPrescription nicotinic acid, 500 mg per tablet
Niacor is an immediate-release prescription nicotinic acid tablet for labeled lipid-disorder uses. Nicotinic acid is a form of vitamin B3; it is different from NR, NMN and nicotinamide. Niacor is included to explain the medical-use boundary, not as a longevity shopping recommendation.
Its prescribing information includes liver, blood-glucose, uric-acid and flushing concerns. Immediate-release and extended-release niacin formulations cannot be treated as interchangeable in a product comparison.
Which details become important when an oral supplement is compared with an infusion service?
Reader Questions
A few questions to consider while reading the evidence.
- Which distinction made the marketplace easier to understand: ingredient, route or intended medical use?
- What would you want a clinic to explain about the exact service behind its headline claim?
Extra Insights & Sources
For readers who want the evidence and comparison details behind this guide.
Product comparison matrix
How do the products and services compare?
This matrix summarizes the product profiles above. Amounts describe the named label or service, not a personal treatment plan. It is not a scorecard or ranking.
| Question | Tru Niagen 300 mg | Elysium Basis | Renue by Science NMN Liposomal Capsules | NADclinic IV NAD+ therapy | Niacor 500 mg nicotinic acid tablets — prescription comparator |
|---|---|---|---|---|---|
| Compound / offering | NR chloride | NR + pterostilbene | Liposomal NMN capsules | IV NAD+ service | Nicotinic acid |
| Selected route | Oral capsule | Oral capsule | Oral capsule | Infusion into a vein | Oral prescription tablet |
| Amount described | 300 mg per capsule | 250 mg NR + 50 mg pterostilbene / 2 capsules | 500 mg NMN / 2 capsules | Depends on exact local service | 500 mg per tablet |
| Role in comparison | Single NR formulation | Combination supplement | Distinct NMN delivery claim | Medical-service route | Prescription-use comparator |
Sources
- NAD+ Supplements
- Safety and regulatory source
- Niacor prescribing information
- Tru Niagen 300 mg — official listing
- Elysium Basis — official listing
- Renue by Science NMN Liposomal Capsules — official listing
- NADclinic IV NAD+ therapy — official listing
- Niacor 500 mg nicotinic acid tablets — prescription comparator — official listing
Image credits
Disclosures
Product descriptions draw on the named companies’ labels and materials. Benefit claims are attributed to their source; inclusion is not an endorsement or a personal treatment recommendation.