Product Guides / Tests and Tech
At-Home Longevity Test Guide
Humanic Blue’s Longevity365 guide: A saliva kit, a blood spot and a stool sample can all arrive in the mail. They do not reveal the same things. These five offerings range from calculated age reports to measured blood markers and gut-microbe profiles.
Explore the productsFor readers interested in living longer and better, the first distinction is what a test measures and what its software calculates from the sample.
01 / Our approach
How did we evaluate these products and services?
We compared company-described samples, report contents, membership requirements and availability. An age estimate, a laboratory measurement and a diagnosis answer different questions.
Best At-Home Longevity Tests: evidence and sources02 / The takeaways
What did the source evidence show?
- TruAge and Index calculate age reports from DNA methylation; GlycanAge uses sugar patterns on immune proteins.
- InsideTracker uses a professional blood draw. Its optional age analysis is separate from the measured blood results.
- ZOE’s verified UK stool kit describes gut microbes, not biological age.
What would change if a reported marker were estimated from DNA patterns rather than measured directly?
The products and services
What is distinct about each product or service?
The order is not a ranking. The profiles distinguish the sample, report and access route for each named offering.
The matrix compares sample collection and the kind of information returned; it does not rank clinical value.
Product 01 / 05
TruDiagnostic TruAge Test
Service formatHome finger-prick blood spot
TruDiagnostic says TruAge uses DNA methylation—chemical tags on DNA—to estimate biological age, aging speed and ages for eleven organ systems. Current report names include OMICmAge, DunedinPACE and SYMPHONYAge.
The sample is mailed back and results appear in a secure portal. Some report items estimate blood markers or physical performance from DNA patterns; they are not direct blood-chemistry, grip-strength or walking tests. The current name is TruAge Test, at the former COMPLETE web address.
Product 02 / 05
Elysium Index
Service formatHome saliva kit
Elysium says Index uses DNA methylation in a saliva sample to report biological age, cumulative rate of aging and nine system ages, including heart, brain and metabolic systems. The kit is collected at home and results appear in an account report.
The company says Index is not FDA approved and is not intended to diagnose disease or assess disease risk. A system-age label is the company’s calculation, rather than an examination of that organ.
Product 03 / 05
GlycanAge Test
Service formatHome finger-prick kit with consultation
GlycanAge analyzes sugar structures attached to immune proteins in blood. The company says those patterns reflect inflammation-related aging and uses them to calculate a biological-age result and additional glycan indexes.
This is a different method from DNA methylation. The package includes a report and specialist video consultation. An inflammation-related pattern does not identify a particular disease.
Product 04 / 05
InsideTracker Ultimate with optional InnerAge2.0
Service formatProfessional blood draw; membership and optional analysis
InsideTracker Ultimate measures blood markers across ten company-defined healthspan categories. InnerAge2.0 is a separate age-style analysis that can be added to the panel; the company compares selected markers with people of the same age and biological sex.
Ultimate requires active membership. Collection is a professional blood draw at Quest or an eligible mobile appointment, rather than a self-collected finger-prick kit. InnerAge2.0 is also sold with a standalone draw.
Product 05 / 05
ZOE Gut Health Test — UK offering
Service formatHome stool kit and active app membership
ZOE says DNA sequencing of a stool sample produces microbiome scores and food suggestions. Its UK offer includes app results and requires an active app membership. This describes gut microbes, rather than calculating biological age.
The verified kit offer ships in the UK. The US site describes the new program as coming soon. This stool-only offering should not be confused with earlier ZOE packages involving blood samples or glucose sensors.
Does the sample answer the question you had before opening the product page?
Reader Questions
A few questions to consider while reading the evidence.
- Which difference would change what you expect to learn from a result?
- What question would still need an answer after the report arrives?
Extra Insights & Sources
For readers who want the evidence and comparison details behind this guide.
Product comparison matrix
How do the products and services compare?
This matrix summarizes the product profiles above. Amounts describe the named label or service, not a personal treatment plan. It is not a scorecard or ranking.
| Question | TruDiagnostic TruAge Test | Elysium Index | GlycanAge Test | InsideTracker Ultimate with optional InnerAge2.0 | ZOE Gut Health Test — UK offering |
|---|---|---|---|---|---|
| Sample | Finger-prick blood spot | Saliva | Finger-prick blood | Professional blood draw | Stool |
| Company-described output | DNA-based age and pace reports | DNA-based age and nine system ages | Glycan-based age and indexes | Blood markers; optional InnerAge2.0 | Microbiome scores and food suggestions |
| Access distinction | Mail-in kit and portal | Mail-in kit and account | Kit plus video consultation | Active Ultimate membership; age analysis extra | Verified UK kit; app membership |
Sources
- Best At-Home Longevity Tests
- TruDiagnostic TruAge Test — official listing
- Elysium Index — official listing
- GlycanAge Test — official listing
- InsideTracker Ultimate with optional InnerAge2.0 — official listing
- ZOE Gut Health Test — UK offering — official listing
Image credits
Disclosures
Product descriptions and report claims are attributed to the named companies. Inclusion is not an endorsement or a recommendation to order testing.