Product Guides / Tests and Tech

Biological Age Test Shopping Guide

Humanic Blue’s Longevity365 guide: Biological-age tests share a label while using different samples and calculations. TruAge and Index use DNA patterns, GlycanAge studies sugar structures on immune proteins, and InnerAge2.0 works from ordinary blood markers.

Explore the products

For readers interested in living longer and better, the first distinction is what a test measures and what its software calculates from the sample.

01 / Our approach

How did we evaluate these products and services?

We compared company-described samples, report contents, membership requirements and availability. An age estimate, a laboratory measurement and a diagnosis answer different questions.

Best Biological Age Tests: evidence and sources

02 / The takeaways

What did the source evidence show?

  • TruAge uses a blood spot and Index uses saliva, although both analyze DNA methylation.
  • GlycanAge includes a specialist consultation and uses a different biological signal.
  • InnerAge2.0 can be added to Ultimate or purchased with its own professional blood draw.

What does an age number leave out about the method used to calculate it?

The products and services

What is distinct about each product or service?

The order is not a ranking. The profiles distinguish the sample, report and access route for each named offering.

The matrix compares sample collection and the kind of information returned; it does not rank clinical value.

Manufacturer image of TruDiagnostic TruAge Test
TruDiagnostic TruAge TestTruDiagnostic TruAge Test. Official product image; packaging claims belong to the manufacturer.
Manufacturer image of Elysium Index
Elysium IndexElysium Index. Official product image; packaging claims belong to the manufacturer.
Manufacturer image of GlycanAge Test
GlycanAge TestGlycanAge Test. Official product image; packaging claims belong to the manufacturer.
Guide option

Product 01 / 04

TruDiagnostic TruAge Test

Service formatHome finger-prick blood spot

TruDiagnostic says TruAge uses DNA methylation—chemical tags on DNA—to estimate biological age, aging speed and ages for eleven organ systems. Current report names include OMICmAge, DunedinPACE and SYMPHONYAge.

The sample is mailed back and results appear in a secure portal. Some report items estimate blood markers or physical performance from DNA patterns; they are not direct blood-chemistry, grip-strength or walking tests. The current name is TruAge Test, at the former COMPLETE web address.

Guide option

Product 02 / 04

Elysium Index

Service formatHome saliva kit

Elysium says Index uses DNA methylation in a saliva sample to report biological age, cumulative rate of aging and nine system ages, including heart, brain and metabolic systems. The kit is collected at home and results appear in an account report.

The company says Index is not FDA approved and is not intended to diagnose disease or assess disease risk. A system-age label is the company’s calculation, rather than an examination of that organ.

Guide option

Product 03 / 04

GlycanAge Test

Service formatHome finger-prick kit with consultation

GlycanAge analyzes sugar structures attached to immune proteins in blood. The company says those patterns reflect inflammation-related aging and uses them to calculate a biological-age result and additional glycan indexes.

This is a different method from DNA methylation. The package includes a report and specialist video consultation. An inflammation-related pattern does not identify a particular disease.

Guide option

Product 04 / 04

InsideTracker InnerAge2.0

Service formatBlood-marker age analysis

InsideTracker says InnerAge2.0 calculates an age-style score from selected blood markers: seventeen for men and thirteen for women. It compares those results with age and biological-sex peers.

It can be bought with a professional lab or mobile draw, or added to an existing Ultimate test. A professional home blood draw differs from collecting a finger-prick sample yourself. This is not a DNA methylation test.

Would a consultation or a particular sample route change the experience of receiving a result?

Before you decide

Where is the full evidence?

The company’s definition of age matters more than whether two reports print a similar-looking number.

The companion article puts these services in the wider context of living longer and better, including what the research can and cannot say about the results.

Best Biological Age Tests: full article and sources

A NOTE FROM LONGEVITY365

We read research, consult expert perspectives and work to make complicated health information easier to understand. What you're reading here reflects how we've interpreted and organized that information. It is educational content—not personal medical advice, diagnosis or treatment guidance.

We're not perfect, and neither is the available research. Evidence changes, new studies emerge and what's appropriate for one person may not be appropriate for another.

Use this article as a starting point for your own research and conversations with qualified professionals. Always talk with your doctor or another trusted healthcare professional before making decisions that could affect your health, particularly if you take medications, are receiving treatment, have existing health conditions, are pregnant or have other circumstances that could affect what's appropriate for you.

Reader Questions

A few questions to consider while reading the evidence.

  1. Which difference would change what you expect to learn from a result?
  2. What question would still need an answer after the report arrives?

Extra Insights & Sources

For readers who want the evidence and comparison details behind this guide.

Product comparison matrix

How do the products and services compare?

This matrix summarizes the product profiles above. Amounts describe the named label or service, not a personal treatment plan. It is not a scorecard or ranking.

QuestionTruDiagnostic TruAge TestElysium IndexGlycanAge TestInsideTracker InnerAge2.0
SampleBlood spotSalivaFinger-prick bloodProfessional blood draw
Signal analyzedDNA methylationDNA methylationGlycans on immune proteinsSelected blood markers
Report / supportAge, pace and system estimatesAge, cumulative rate and system estimatesAge indexes and video consultationAge-style comparison with peers

Sources

Image credits

Disclosures

Product descriptions and report claims are attributed to the named companies. Inclusion is not an endorsement or a recommendation to order testing.

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