Bone Health

When Should Women Get a Bone Density Test?

US guidance recommends bone-density screening for women 65 and older, and younger postmenopausal women whose risk assessment indicates increased risk.

10 min read · Longevity365 Editorial

In the United States, the US Preventive Services Task Force (USPSTF) recommends osteoporosis screening for women age 65 or older. Osteoporosis weakens bones and makes fractures more likely. The Task Force also recommends screening postmenopausal women younger than 65 when they have at least one risk factor and a clinical risk-assessment tool indicates increased fracture risk.

A previous fragility fracture, a bone-weakening condition or long-term use of a bone-depleting medication can call for evaluation outside routine screening. A fragility fracture is a break after a fall from standing height or less that would not usually break healthy bone. Humanic Blue keeps the paths distinct: screening looks for a problem before it is known, while diagnostic evaluation investigates a fracture or suspected bone loss.

For living longer and better, the reason to test is not to collect another score. It is to find high fracture risk early enough for evaluation and, when appropriate, treatment. A central DXA scan, a low-dose X-ray measurement of bone density at the hip and spine, is the standard test. It is quick and uses a small amount of radiation, but its result is not a complete forecast: age, falls, medications, prior fractures and other risks also matter.

Key Takeaways

  • US guidance recommends screening women at age 65, even without an obvious risk factor.
  • After menopause but before 65, screening is recommended when a two-step risk assessment identifies increased fracture risk.
  • A DXA T-score measures bone density; it does not capture every cause of fracture or determine treatment by itself.

When does routine bone-density screening begin?

The USPSTF’s 2025 recommendation recommends osteoporosis screening for women age 65 and older to prevent fractures. For this B-grade recommendation, the Task Force concluded with moderate certainty that screening has a moderate overall benefit. For postmenopausal women younger than 65, it recommends a two-step approach.

First, a clinician looks for one or more risk factors in addition to postmenopausal status. The USPSTF names low body weight, a parental history of hip fracture, cigarette smoking and excess alcohol consumption. Second, a validated clinical risk-assessment tool estimates whether risk is high enough to proceed to DXA.

This is not a recommendation for every woman to schedule a scan on her first day of menopause. It is also not a recommendation to wait until 65 regardless of health history. Age 65 is the routine-screening threshold; younger postmenopausal women move through a risk pathway.

The recommendation applies to adults age 40 or older without known osteoporosis or a previous fragility fracture. It does not cover people whose bone loss may come from conditions such as cancer, hyperthyroidism (an overactive thyroid) or metabolic bone disease (disorders of how the body builds or maintains bone), or from chronic use of glucocorticoids, a class of steroid medicines. These are possible causes of secondary osteoporosis—bone weakening linked to another condition or medication. Those situations need individualized clinical evaluation rather than a routine-screening calendar.

Menopause explains why risk review starts earlier than many expect

Estrogen helps regulate the ongoing replacement of old bone with new bone. The American College of Obstetricians and Gynecologists (ACOG) says the fall in estrogen around menopause triggers a period of rapid bone loss beginning about one year before the final menstrual period and lasting for roughly three years.

Researchers in the Study of Women’s Health Across the Nation (SWAN), led by geriatrician Gail Greendale, MD, followed about 900 women through the final menstrual period. Average bone-density loss was greatest from one year before to two years after that period. Most of the decline recorded across ten years happened in that three-year window (SWAN bone analysis).

Those averages do not predict one person’s loss. Body size, ancestry, medications, illness, physical activity and starting bone mass all affect the trajectory. The study also measured density, not fractures, and does not by itself prove that routine DXA during perimenopause improves outcomes.

What can call for testing before 65?

A clinician may use the FRAX tool, developed from population-based cohorts by researchers at the University of Sheffield, to estimate the chance of a hip fracture or a major osteoporotic fracture (hip, spine, wrist or shoulder) over the next ten years. FRAX combines age and other clinical factors and can be calculated with or without bone density at the femoral neck, the narrow part of the thigh bone near the hip.

The USPSTF also lists the Osteoporosis Risk Assessment Instrument and Osteoporosis Self-assessment Tool as examples. It does not endorse one universal FRAX percentage as the screening cutoff for every US woman under 65. The tool and threshold need clinical context.

SituationWhat current US guidance supportsWhy the route differs
Woman age 65 or older without known osteoporosisOsteoporosis screening with central DXA, with or without fracture-risk assessmentAge alone meets the USPSTF screening recommendation
Postmenopausal woman younger than 65 with a risk factorClinical risk assessment first; DXA if estimated risk is increasedNot every younger postmenopausal woman receives routine imaging
Previous low-trauma or fragility fractureClinical evaluation rather than ordinary screeningA fracture may already indicate skeletal fragility
Long-term use of glucocorticoid steroid medicines or a bone-affecting conditionIndividualized diagnostic and management pathwayThe USPSTF screening recommendation excludes secondary osteoporosis
Premenopausal woman without unusual fractures or secondary riskRoutine population screening is not part of the USPSTF pathway; the clinical densitometry society identifies specific reasons for testingThe International Society for Clinical Densitometry recommends age-based Z-score comparisons rather than young-adult T-score comparisons before menopause and identifies specified risks for testing

The Bone Health and Osteoporosis Foundation also recommends DXA for women age 65 and older and for women ages 50 to 64 with risk factors. Different professional groups phrase the younger-age pathway differently, which is one reason a risk assessment is more useful than a blanket “scan at menopause” rule.

Which risk-assessment details determine the scope of the earlier-screening guidance?

A DXA scan measures density at the sites that matter most

The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), part of the US National Institutes of Health, describes central dual-energy X-ray absorptiometry—DXA or DEXA—as the most reliable way to diagnose osteoporosis and help predict fracture risk. It generally measures the hip and spine while a person lies on a padded table.

ACOG says the scan usually takes three to ten minutes and exposes a person to less radiation than a standard chest X-ray. It is noninvasive and painless.

Heel ultrasound and peripheral scans can help identify risk, but NIAMS says an abnormal heel ultrasound still requires central DXA to diagnose osteoporosis. Consumer body-composition scans may report “bone mass,” but that number is not a substitute for a clinical hip-and-spine DXA.

The T-score is useful, but it is not the whole fracture story

For postmenopausal women, DXA results are commonly expressed as a T-score—a comparison with the bone density of a healthy young adult. The number describes how far a result is above or below that reference average, in statistical units called standard deviations. It is not a percentage of bone lost. NIAMS describes the usual categories:

  • −1.0 or higher: bone density in the normal range.
  • Below −1.0 but above −2.5: low bone mass, often called osteopenia.
  • −2.5 or lower: a result consistent with osteoporosis in the appropriate clinical setting.

Fracture risk does not begin at −2.5. The USPSTF notes that many fragility fractures occur in people whose T-scores are above the osteoporosis threshold. Age can produce very different fracture risks in two people with the same density because falls, bone quality and competing health risks also change over time.

That is the counter-case to treating the scan as a verdict. A low score deserves interpretation, but a “normal” score does not make falls irrelevant. A treatment decision may incorporate prior hip or spine fracture, calculated fracture probability, medical conditions, kidney function, medication risks and patient priorities—not only the lowest number on the report.

What does a density score leave out of a fracture-risk estimate?

When should a DXA scan be repeated?

ACOG says the interval after an initial test depends on age, the prior DXA result and individual fracture risk. Treatment monitoring follows a different schedule from repeat screening in someone whose first result was normal.

The evidence base does not support one repeat interval for everyone. The USPSTF’s 2025 evidence review found that, across five studies including about 20,000 people, repeating bone density four to eight years after the first test added little to prediction compared with the baseline result alone (USPSTF evidence summary). The review called that evidence indirect, and study quality ranged from poor to fair.

Testing too frequently can produce an apparent change smaller than a facility’s calculated least significant change—the threshold used to distinguish a likely biological change from measurement variability. The International Society for Clinical Densitometry says each facility should calculate its own precision error and that repeat intervals should be individualized. Waiting too long may be inappropriate after a fracture or a major health or medication change. The ordering clinician or osteoporosis specialist can use the baseline score and the reason for testing to set an interval.

Screening has a benefit only if the result changes care

The USPSTF describes a pathway from identifying osteoporosis to further evaluation, counseling and, when appropriate, evidence-based treatment. Screening itself does not strengthen bone.

The Task Force concluded that screening the women covered by its recommendation has a moderate net benefit, although the direct screening trials enrolled older European women and did not test DXA-only screening. Possible harms include overdiagnosis—finding low bone density that would never cause a clinical problem—and harms from subsequent treatment; evidence about the size of those harms is limited. In the one screening trial that measured anxiety, anxiety did not differ between groups over five years. DXA radiation is low, so the larger practical issue is whether the finding is interpreted correctly and leads to care that fits the person’s fracture risk.

The guideline also notes that only 40% to 60% of people who experience a hip fracture recover their previous mobility and ability to perform daily activities. That consequence—not the attractiveness of a higher score—is why fracture prevention matters.

What’s Interesting

Researchers are studying whether blood markers and reproductive hormones could identify fast bone loss before a routine scan would normally be ordered. A 2026 SWAN analysis of about 400 early-perimenopausal women found that lower anti-Müllerian hormone, a marker of ovarian activity, and higher collagen type I C-telopeptide, a marker of bone breakdown, were associated with a greater chance of rapid bone loss over the next one to two years (2026 SWAN analysis).

That is emerging risk-prediction research, not a new population-screening standard. The study assessed near-term density decline rather than whether biomarker-guided testing prevents fractures. No major US guideline currently recommends those markers as routine substitutes for clinical risk assessment and DXA.

What This Means in Practice

The USPSTF’s routine screening recommendation begins at 65. After menopause but before 65, its pathway begins with risk factors, followed by a formal risk estimate to help decide whether DXA is warranted. At any age, a low-trauma fracture, substantial unexplained height loss, long-term glucocorticoid use or a condition associated with bone loss deserves a clinical conversation outside the routine timetable.

For living longer and better, the connection runs through fracture prevention, mobility and independence—not through a scan that adds years by itself. A clinician can also review fall risk, resistance and weight-bearing activity, calcium and vitamin D intake, smoking, alcohol, medications and treatment options. Those decisions depend on the whole risk profile, not on buying the most frequent scan available.

For what happens during the scan and how to read the report, DEXA Scans Explained is the next layer.

Bottom Line

US guidance recommends bone-density screening for women at 65 and for younger postmenopausal women whose risk assessment shows increased fracture risk. Earlier diagnostic evaluation may be appropriate after a fragility fracture or with bone-affecting conditions or medications. Central hip-and-spine DXA is the standard test, but its T-score is one part of the decision. The cited authorities interpret the result alongside age, fracture history, fall risk and medical context; repeat timing depends on the first result and the reason for testing.

A NOTE FROM LONGEVITY365

We read research, consult expert perspectives and work to make complicated health information easier to understand. What you’re reading here reflects how we’ve interpreted and organized that information. It is educational content—not personal medical advice, diagnosis or treatment guidance.

We’re not perfect, and neither is the available research. Evidence changes, new studies emerge and what’s appropriate for one person may not be appropriate for another.

Use this article as a starting point for your own research and conversations with qualified professionals. Always talk with your doctor or another trusted healthcare professional before making decisions that could affect your health, particularly if you take medications, are receiving treatment, have existing health conditions, are pregnant or have other circumstances that could affect what’s appropriate for you.

Reader Questions

A few questions to carry into the comments or your next conversation. Please leave out identifying or personal medical details.

  • 01After reading this, what would you want a test result to actually help you decide?
  • 02How does the distinction between routine screening and evaluation after a low-trauma fracture change your understanding of when testing might be discussed?
  • 03What would you ask a clinician, lab, or qualified professional before letting a number change a health decision?

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Extra Insights & Sources

The evidence summaries and linked sources behind this article.

What We Know

  • Screening women age 65 and older, and higher-risk postmenopausal women younger than 65, is recommended by the USPSTF.
  • Bone loss accelerates around the final menstrual period in longitudinal SWAN data. Supported.
  • Central hip-and-spine DXA is the standard density test for diagnosing osteoporosis. Established.
  • Bone density, age and clinical risks together predict fracture better than density alone. Established.

What We Don’t Know

  • One ideal age for every woman below 65 to receive a first scan. Individualized by risk.
  • One best interval for repeat screening after a normal result. Uncertain and risk-dependent.
  • Whether routine DXA in average-risk perimenopause improves fracture outcomes. Not established.
  • Whether a bone density test itself helps anyone live longer. Unsupported; benefit depends on what follows the result.

Source Materials

  • US Preventive Services Task Force, Osteoporosis to Prevent Fractures: Screening (2025) — Current US recommendation supporting screening for women 65 and older and a two-step risk-factor and risk-tool pathway for postmenopausal women younger than 65. It applies to adults 40 and older without known osteoporosis or a fragility fracture and excludes secondary osteoporosis from conditions or chronic bone-depleting medication use. The Task Force found moderate net benefit for the women covered, but insufficient evidence for men.
  • Kahwati et al., USPSTF evidence summary (2025) — Systematic review searched major databases through January 9, 2024, with surveillance through July 31, 2024. Three screening trials in 42,009 older, higher-risk European women found 5 to 6 fewer hip or major osteoporotic fractures per 1,000 screened; no trial evaluated DXA-only screening, men or younger women. Five cohort studies (19,957 participants; mean ages 60–75) found repeat BMD at four to eight years added little fracture-prediction accuracy; two studies were poor quality, three fair, and the evidence was indirect. One trial found no anxiety difference over five years, while evidence on overdiagnosis was insufficient.
  • American College of Obstetricians and Gynecologists, Osteoporosis — Current patient guidance supporting BMD testing at 65 and risk-based testing after menopause before 65. It describes DXA as a three-to-ten-minute test with less radiation than a conventional chest X-ray and says repeat timing depends on age, prior results and individual fracture risk. This is professional guidance, not a primary study.
  • Greendale et al., SWAN bone-loss analysis (2012) — Longitudinal observational analysis of 862 Black, White, Chinese and Japanese women followed from five years before to five years after the final menstrual period. Average ten-year BMD loss was 10.6% at the lumbar spine and 9.1% at the femoral neck, with the fastest loss from one year before through two years after the final menstrual period. It measured BMD rather than fractures and cannot establish that perimenopausal screening improves outcomes.
  • FRAX/FRAXplus official calculator — Current home of the country-specific models that combine clinical risk factors, with or without femoral-neck BMD, to estimate ten-year hip and major osteoporotic-fracture probability. FRAX is a risk-estimation aid, not a diagnosis or a universal USPSTF screening threshold; its inputs omit or simplify some risks.
  • Bone Health and Osteoporosis Foundation, Evaluation of Bone Health/Bone Density Testing — Nonprofit clinical guidance recommending testing for women 65 and older and women 50–64 with risk factors, including family history, falls, smoking, excess alcohol, malabsorption and some medications. Its younger-age wording is broader than the USPSTF’s two-step recommendation.
  • National Institute of Arthritis and Musculoskeletal and Skin Diseases, Osteoporosis: Diagnosis, Treatment, and Steps to Take — NIH patient guidance describing central hip-and-spine DXA as the most reliable common method for diagnosing osteoporosis and predicting fracture risk. It also explains that heel ultrasound does not measure BMD and that an abnormal result still requires DXA for diagnosis.
  • NIAMS, Bone Mineral Density Tests: What the Numbers Mean — NIH explanation of central DXA and the usual postmenopausal T-score categories: normal at −1 or higher, low bone mass from −1 to −2.5, and possible osteoporosis at −2.5 or lower. It specifies Z-scores for premenopausal women and does not make a T-score the sole measure of fracture risk.
  • International Society for Clinical Densitometry, Adult Official Positions (2023) — Professional consensus positions on who should receive BMD testing, use of Z-scores before menopause, central DXA sites, follow-up testing and facility-specific precision error/least significant change. These positions support clinically indicated testing during the menopause transition and individualized repeat intervals; they are consensus guidance rather than outcome trials.
  • Shieh et al., 2026 SWAN biomarker analysis — Repeated-measures observational analysis of 436 early-perimenopausal SWAN participants. Lower AMH and higher CTX independently predicted a higher risk of fast lumbar-spine, femoral-neck or total-hip BMD decline over the next one to two years; the outcome was BMD decline, not fracture prevention, and the findings do not establish routine biomarker screening. The article reports publication by Oxford University Press for the Endocrine Society; no author conflict statement was available in the PubMed record reviewed.

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