
Vitamin D Testing
The Endocrine Society advises against routine vitamin D testing in healthy adults; the USPSTF says evidence is insufficient. Clinical indications still matter.
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The Endocrine Society advises against routine vitamin D testing in healthy adults; the USPSTF says evidence is insufficient. Clinical indications still matter.
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hs-CRP measures low-grade inflammation. At 2 mg/L or higher, it flags added heart risk and can tip a statin decision. Genetics suggest CRP itself isn't a cause.
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Under 150 mg/dL is the fasting reference. Above it, triglycerides flag heart risk; above 500, pancreatitis. Lowering them alone hasn't reliably cut events.
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Fasting glucose has diagnostic cutoffs. Fasting insulin has no universal cutoff for insulin resistance; the tests serve different roles in clinical care.
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HbA1c tracks blood sugar and predicts heart disease and death. But lower isn't always better, and prediabetes often doesn't progress in older adults.
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Lp(a) is a mostly inherited particle linked to heart attack, stroke and aortic stenosis. US guidance says every adult should be tested at least once.
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ApoB estimates the number of cholesterol-carrying particles that can enter artery walls. It can reveal risk that LDL cholesterol alone may understate.
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Kidney function, TSH, HbA1c and hemoglobin all shift with age. Some shifts are normal aging; others signal disease. Most lab ranges don't adjust for age.
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A practical checklist for longevity bloodwork: how to prepare, what can skew results, and how to read and track your numbers over time.
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Guideline-backed longevity bloodwork is short: lipids, a diabetes test, one-time Lp(a) and infection screens. No trial shows bigger panels add years.
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